| http://purl.uniprot.org/citations/11136710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11136710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11136710 | http://www.w3.org/2000/01/rdf-schema#comment | "Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disease caused by the expansion of a polyglutamine tract within the SCA1 product, ataxin-1. Previously, using transgenic mice, it was demonstrated that in order for a mutant allele of ataxin-1 to cause disease it must be transported to the nucleus of the neuron. Using an in vitro RNA-binding assay, we demonstrate that ataxin-1 does bind RNA and that this binding diminishes as the length of its polyglutamine tract increases. These observations suggest that ataxin-1 plays a role in RNA metabolism and that the expansion of the polyglutamine tract may alter this function."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/10.1.25"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/10.1.25"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Orr H.T."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Orr H.T."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Zoghbi H.Y."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Zoghbi H.Y."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Serra H.G."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Serra H.G."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Yue S."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/author | "Yue S."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/name | "Hum. Mol. Genet."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/name | "Hum. Mol. Genet."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/pages | "25-30"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/pages | "25-30"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/title | "The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/title | "The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract."xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/11136710 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11136710 |
| http://purl.uniprot.org/citations/11136710 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11136710 |