| http://purl.uniprot.org/citations/11150242 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11150242 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11150242 | http://www.w3.org/2000/01/rdf-schema#comment | "Cyclin B mRNA stored in immature zebrafish oocytes is translationally activated upon the stimulation of 17alpha,20beta-dihydroxy-4-pregnen-3-one (17alpha,20beta-DP), an event prerequisite for initiating oocyte maturation in this species. We investigated localization of cyclin B mRNA in zebrafish oocytes. Cyclin B mRNA was found to be exclusively localized as an aggregation along the cytoplasm at the animal pole of full-grown immature oocytes. When oocytes were treated with 17alpha,20beta-DP, a meshwork of microfilaments in the oocyte cortex disappeared and the aggregation of cyclin B mRNA dispersed just prior to the initiation of cyclin B synthesis and germinal vesicle breakdown (GVBD). Cytochalasin B, but not nocodazole or taxol, deformed the aggregation of cyclin B mRNA, indicating the involvement of microfilaments in organizing this form. Like 17alpha,20beta-DP, cytochalasin B (10 microg/ml) induced both complete dispersion of the aggregation and translational activation of cyclin B mRNA, forcing the oocytes to undergo GVBD without 17alpha,20beta-DP. Conversely, disturbance of the aggregation of cyclin B mRNA with a low concentration (1 microg/ml) of cytochalasin B inhibited 17alpha,20beta-DP-induced GVBD. These results suggest that the direct change in cyclin B mRNA from the aggregated form to the dispersed form is responsible for translational activation of the mRNA during zebrafish oocyte maturation."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2000.9990"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Yamashita M."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Yamashita M."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Kotani T."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Kotani T."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Kondo T."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/author | "Kondo T."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/pages | "421-431"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/pages | "421-431"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/title | "Dispersion of cyclin B mRNA aggregation is coupled with translational activation of the mRNA during zebrafish oocyte maturation."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/title | "Dispersion of cyclin B mRNA aggregation is coupled with translational activation of the mRNA during zebrafish oocyte maturation."xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/volume | "229"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://purl.uniprot.org/core/volume | "229"xsd:string |
| http://purl.uniprot.org/citations/11150242 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11150242 |
| http://purl.uniprot.org/citations/11150242 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11150242 |
| http://purl.uniprot.org/citations/11150242 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11150242 |
| http://purl.uniprot.org/citations/11150242 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11150242 |
| http://purl.uniprot.org/uniprot/Q9IB44 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/11150242 |