| http://purl.uniprot.org/citations/11159918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11159918 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11159918 | http://www.w3.org/2000/01/rdf-schema#comment | "Glycosylphosphatidylinositol (GPI) anchors of all species contain the core structure protein-CO-NH-(CH(2))(2)-PO(4)-Manalpha1-2Manalpha1-6Manalpha1-4GlcNalpha1-6inositol-PO(4)-lipid. In recent studies in yeast it was found that gpi10-1 mutants accumulate M2, an abnormal intermediate having the structure Manalpha1-6[NH(2)-(CH(2))(2)-PO(4)-->]Manalpha1-4GlcNalpha1-6(acyl-->)inositol-PO(4)-lipid. It thus was realized that yeast GPI lipids, as their mammalian counterparts, contain an additional phosphorylethanolamine side chain on the alpha1,4-linked mannose. The biosynthetic origin of this phosphorylethanolamine group was investigated using gpi10-1 Deltaept1 Deltacpt1, a strain which is unable to synthesize phosphatidylethanolamine by transferring phosphorylethanolamine from CDP-ethanolamine onto diacylglycerol, but which still can make phosphatidylethanolamine by decarboxylation of phosphatidylserine. Gpi10-1 Deltaept1 Deltacpt1 triple mutants are unable to incorporate [(3)H]ethanolamine into M2 although metabolic labeling with [(3)H]inositol demonstrates that they make as much M2 as gpi10-1. In contrast, when labeled with [(3)H]serine, the triple mutant incorporates more label into M2 than gpi10-1. This result establishes that the phosphorylethanolamine group on the alpha1,4-linked mannose is derived from phosphatidylethanolamine and not from CDP-ethanolamine."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.org/dc/terms/identifier | "doi:10.1093/glycob/10.12.1271"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.org/dc/terms/identifier | "doi:10.1093/glycob/10.12.1271"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Conzelmann A."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Conzelmann A."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Imhof I."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Imhof I."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Meyer U."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Meyer U."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Canivenc-Gansel E."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/author | "Canivenc-Gansel E."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/date | "2000"xsd:gYear |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/name | "Glycobiology"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/name | "Glycobiology"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/pages | "1271-1275"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/pages | "1271-1275"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/title | "Phosphatidylethanolamine is the donor of the phosphorylethanolamine linked to the alpha1,4-linked mannose of yeast GPI structures."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/title | "Phosphatidylethanolamine is the donor of the phosphorylethanolamine linked to the alpha1,4-linked mannose of yeast GPI structures."xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://purl.uniprot.org/core/volume | "10"xsd:string |
| http://purl.uniprot.org/citations/11159918 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11159918 |
| http://purl.uniprot.org/citations/11159918 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11159918 |