| http://purl.uniprot.org/citations/11161574 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11161574 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11161574 | http://www.w3.org/2000/01/rdf-schema#comment | "This study presents Xenopus claudin (Xcla), a tight-junction protein that is abundantly expressed in eggs and neuroectodermal precursors during early development. It was isolated via a differential screen for mRNAs enriched in microsomes in the Xenopus blastula. The Xcla protein contains four transmembrane domains and a carboxy-terminal cytoplasmic region with a putative PDZ-binding site. We show that this PDZ-binding site of Xcla is critical for its correct localization on the cell membrane and that a truncated form leads to delocalization of the tight-junction protein ZO-1. Overexpression of Xcla causes changes in the cell adhesion properties of blastomeres and leads to visceral situs randomization. The results suggest that left-right axial patterning is very sensitive to changes in regulation of cell-cell interactions and implicate a tight-junction protein in the determination of left-right asymmetry."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2000.0116"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.2000.0116"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "Brizuela B.J."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "Brizuela B.J."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "De Robertis E.M."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "De Robertis E.M."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "Wessely O."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/author | "Wessely O."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/name | "Dev. Biol."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/pages | "217-229"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/pages | "217-229"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/title | "Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/title | "Overexpression of the Xenopus tight-junction protein claudin causes randomization of the left-right body axis."xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/volume | "230"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://purl.uniprot.org/core/volume | "230"xsd:string |
| http://purl.uniprot.org/citations/11161574 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11161574 |
| http://purl.uniprot.org/citations/11161574 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11161574 |
| http://purl.uniprot.org/citations/11161574 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11161574 |
| http://purl.uniprot.org/citations/11161574 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11161574 |