| http://purl.uniprot.org/citations/11163241 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11163241 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11163241 | http://www.w3.org/2000/01/rdf-schema#comment | "Synaptic vesicle fusion at synapses is triggered by increases in cytosolic Ca2+ levels. However, the identity of the Ca2+ sensor and the transduction mechanism of the Ca2+ trigger are unknown. We show that Complexins, stoichiometric components of the exocytotic core complex, are important regulators of transmitter release at a step immediately preceding vesicle fusion. Neurons lacking Complexins show a dramatically reduced transmitter release efficiency due to decreased Ca2+ sensitivity of the synaptic secretion process. Analyses of mutant neurons demonstrate that Complexins are acting at or following the Ca2+-triggering step of fast synchronous transmitter release by regulating the exocytotic Ca2+ sensor, its interaction with the core complex fusion machinery, or the efficiency of the fusion apparatus itself."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00192-1"xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00192-1"xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Suedhof T.C."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Suedhof T.C."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Mansour M."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Mansour M."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "McMahon H.T."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "McMahon H.T."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Brose N."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Brose N."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Rosenmund C."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Rosenmund C."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Reim K."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Reim K."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Varoqueaux F."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/author | "Varoqueaux F."xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/pages | "71-81"xsd:string |
| http://purl.uniprot.org/citations/11163241 | http://purl.uniprot.org/core/pages | "71-81"xsd:string |