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http://purl.uniprot.org/citations/11165717http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11165717http://www.w3.org/2000/01/rdf-schema#comment"We have evaluated the possible contribution of genes besides DQ and DR to the association of HLA with rheumatoid arthritis (RA). To this end, we have looked at the allele distributions of six microsatellites, D6S1014, D6S2673, TNFalpha, MIB, C1-2-5, and C1-3-2 among 132 RA patients and 254 controls. We have defined 19 microsatellite clusters corresponding to previously described ancestral haplotypes. One of them was D6S1014*143-D6S273*139-TNFalpha*99-MIB*350-C1-2-5*196-C1-3-2*354, often found associated with DQB1*0201-DRB1*0301. As part of this microsatellite cluster, the allele MIB*350 was found to be a RA-predisposing factor, independent of DRB1*0301 and RA-predisposing haplotypes DQB1*03-DRB1*04 and DQB1*0501-DRB1*01. We conclude that the telomeric part of the HLA region contains a locus conferring predisposition to RA independently of HLA class II."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.org/dc/terms/identifier"doi:10.1016/s0198-8859(00)00227-5"xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Martin J."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Zwinderman A.H."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Pascual M."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Jones G."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Giphart M.J."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Verduyn W."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Roovers E."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Zanelli E."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Schreuder G.M."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Breedveld F.C."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"van der Slik A.R."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"Eerligh P."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/author"de Vries R.R."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/name"Hum Immunol"xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/pages"75-84"xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/title"The telomeric part of the HLA region predisposes to rheumatoid arthritis independently of the class II loci."xsd:string
http://purl.uniprot.org/citations/11165717http://purl.uniprot.org/core/volume"62"xsd:string
http://purl.uniprot.org/citations/11165717http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11165717
http://purl.uniprot.org/citations/11165717http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11165717
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-11165717http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11165717
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-11165717http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11165717