| http://purl.uniprot.org/citations/11169754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11169754 | http://www.w3.org/2000/01/rdf-schema#comment | "The gene pzl-1 from the filamentous fungus Neurospora crassa encodes a putative Ser/Thr protein phosphatase that is reminiscent of the Ppz1/Ppz2 and Pzh1 phosphatases from Saccharomyces cerevisiae and Schizosaccharomyces pombe, respectively. The entire PZL-1 protein, as well as its carboxyl-terminal domain, have been expressed in Escherichia coli as active protein phosphatases. To characterize its cellular role, PZL-1 was also expressed in Sz. pombe and in S. cerevisiae. Expression of PZL-1 in S. cerevisiae from the PPZ1 promoter was able to rescue the altered sensitivity to caffeine and lithium ions of a ppz1 strain. Furthermore, high copy number expression of PZL-1 alleviated the lytic phenotype of a S. cerevisiae slt2/mpk1 mitogen-activated protein (MAP) kinase mutant, similarly to that described for PPZ1, and mimicked the effects of high levels of Ppz1 on cell growth. Expression of PZL-1 in fission yeast from a weak version of the nmt1 promoter fully rescued the growth defect of a pzh1Delta strain in high potassium, but only partially complemented the sodium-hypertolerant phenotype. Strong overexpression of the N. crassa phosphatase in Sz. pombe affected cell growth and morphology. Therefore, PZL-1 appears to fulfil every known function carried out by its S. cerevisiae counterpart, despite the marked divergence in sequence within their NH(2)-terminal moieties."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.org/dc/terms/identifier | "doi:10.1002/1097-0061(20010130)18:2<115::aid-yea653>3.0.co;2-g"xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Dombradi V."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Arino J."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Barcelo A."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "de Nadal E."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Clotet J."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Gergely P."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Vissi E."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/author | "Bako E."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/name | "Yeast"xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/pages | "115-124"xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/title | "Functional analysis of the Neurospora crassa PZL-1 protein phosphatase by expression in budding and fission yeast."xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://purl.uniprot.org/core/volume | "18"xsd:string |
| http://purl.uniprot.org/citations/11169754 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11169754 |
| http://purl.uniprot.org/citations/11169754 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11169754 |
| http://purl.uniprot.org/uniprot/#_P78968-mappedCitation-11169754 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11169754 |
| http://purl.uniprot.org/uniprot/P78968 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11169754 |