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http://purl.uniprot.org/citations/11181388http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11181388http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11181388http://www.w3.org/2000/01/rdf-schema#comment"Falcipain-2, a cysteine protease and essential hemoglobinase of Plasmodium falciparum, is a potential antimalarial drug target. We compared the falcipain-2 sequences and sensitivities to cysteine protease inhibitors of five parasite strains that differ markedly in sensitivity to established antimalarial drugs. The sequence of falcipain-2 was highly conserved, and the sensitivities of all of the strains to falcipain-2 inhibitors were very similar. Thus, cross-resistance between cysteine protease inhibitors and other antimalarial agents is not expected in parasites that are now circulating and falcipain-2 remains a promising chemotherapeutic target."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.org/dc/terms/identifier"doi:10.1128/AAC.45.3.949-951.2001"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.org/dc/terms/identifier"doi:10.1128/aac.45.3.949-951.2001"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/author"Singh A."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/author"Singh A."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/author"Rosenthal P.J."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/author"Rosenthal P.J."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/name"Antimicrob. Agents Chemother."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/name"Antimicrob Agents Chemother"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/pages"949-951"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/pages"949-951"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/title"Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/title"Comparison of efficacies of cysteine protease inhibitors against five strains of Plasmodium falciparum."xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/volume"45"xsd:string
http://purl.uniprot.org/citations/11181388http://purl.uniprot.org/core/volume"45"xsd:string
http://purl.uniprot.org/citations/11181388http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11181388
http://purl.uniprot.org/citations/11181388http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11181388
http://purl.uniprot.org/citations/11181388http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11181388
http://purl.uniprot.org/citations/11181388http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11181388
http://purl.uniprot.org/uniprot/Q9N6S8http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11181388
http://purl.uniprot.org/uniprot/Q9NAW2http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/11181388