| http://purl.uniprot.org/citations/11182042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11182042 | http://www.w3.org/2000/01/rdf-schema#comment | "The c-myc gene is involved in important cellular processes, including cell proliferation, differentiation, and apoptosis. We analyzed mutation of the c-myc gene in 51 patients with gastric lymphoma [27 patients with low-grade mucosa-associated lymphoid tissue (MALT) lymphoma, 11 with high-grade MALT lymphoma, and 13 with diffuse large B-cell lymphoma (DLL)], by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis. We also evaluated the relationship between mutation of the c-myc gene and regression of low-grade MALT lymphoma after Helicobacter pylori (H. pylori) eradication. Mutation in exon 2 of the c-myc gene was present in 2 of 20 (10%) patients with low-grade MALT lymphoma, in 1 of 7 (14%) patients with high-grade MALT lymphoma, and none of 10 patients with DLL. The 3 patients who had mutations of the gene, showed different patterns of mobility shift, suggesting different mutations. In addition, 15 patients with low-grade MALT lymphoma received anti-H. pylori therapy. All the patients achieved eradication. Nine of the 15 (60%) patients with low-grade MALT lymphoma showed complete regression (CR), 3 (20%) showed partial regression (PR), and 3 (20%) showed no change (NC). One of the 9 (11%) CR patients had a mutation of the c-myc gene. None of the 3 PR and 3 NC patients had mutation of the gene. There was no significant difference between the frequencies among the c-myc gene mutation in CR, in PR and in NC patients. These data suggest that mutation of the c-myc gene may not be commonly associated with development of gastric MALT lymphoma and DLL, and may not be associated with regression of low-grade MALT lymphoma after H. pylori eradication."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.org/dc/terms/identifier | "doi:10.3892/or.8.2.289"xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Tanaka S."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Miyamoto M."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Masuda H."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Hiyama T."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Chayama K."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Yoshihara M."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Shimamoto F."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Sumii K."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Haruma K."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/author | "Kitadai Y."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/name | "Oncol Rep"xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/pages | "289-292"xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/title | "c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma."xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/11182042 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11182042 |
| http://purl.uniprot.org/citations/11182042 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11182042 |
| http://purl.uniprot.org/uniprot/#_A0A0B4J1R1-mappedCitation-11182042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11182042 |
| http://purl.uniprot.org/uniprot/#_A0N2G3-mappedCitation-11182042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11182042 |
| http://purl.uniprot.org/uniprot/#_A0A224B085-mappedCitation-11182042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11182042 |
| http://purl.uniprot.org/uniprot/#_B3CJ86-mappedCitation-11182042 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11182042 |