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http://purl.uniprot.org/citations/11182084http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11182084http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11182084http://www.w3.org/2000/01/rdf-schema#comment"In the fly visual system, each class of photoreceptor neurons (R cells) projects to a different synaptic layer in the brain. R1-R6 axons terminate in the lamina, while R7 and R8 axons pass through the lamina and stop in the medulla. As R cell axons enter the lamina, they encounter both glial cells and neurons. The cellular requirement for R1-R6 targeting was determined using loss-of-function mutations affecting different cell types in the lamina. nonstop (encoding a ubiquitin-specific protease) is required for glial cell development and hedgehog for neuronal development. Removal of glial cells but not neurons disrupts R1-R6 targeting. We propose that glial cells provide the initial stop signal promoting growth cone termination in the lamina. These findings uncover a novel function for neuron-glial interactions in regulating target specificity."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(01)00183-0"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(01)00183-0"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Fischer S."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Fischer S."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Zipursky S.L."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Zipursky S.L."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Poeck B."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Poeck B."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Salecker I."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Salecker I."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Gunning D."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/author"Gunning D."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/pages"99-113"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/pages"99-113"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/title"Glial cells mediate target layer selection of retinal axons in the developing visual system of Drosophila."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/title"Glial cells mediate target layer selection of retinal axons in the developing visual system of Drosophila."xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/volume"29"xsd:string
http://purl.uniprot.org/citations/11182084http://purl.uniprot.org/core/volume"29"xsd:string