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http://purl.uniprot.org/citations/11189498http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11189498http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To investigate the relationship between HLA-DQB1 allele and susceptibility to beta-thalassemia in Guangxi Chinese Zhuang nationality.

Methods

The polymorphism of the HLA-DQB1 loci in 64 randomly selected, unrelated Guangxi Zhuang individuals with beta-thalassemia was investigated by PCR-SSP.

Results

Compared with normal controls, the frequency of HLA-DQB1*0604 allele was significantly increased in the patient group, with a relative risk(RR) of 9.9(chi 2 = 20.78, P < 0.005), while the frequencies of other HLA-DQB1 alleles did not in the patient group.

Conclusion

The susceptibility to beta-thalassemia in the Guangxi Zhuang individuals is associated with HLA-DQB1*0604 allele."xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/author"Long G."xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/author"Mohamed A.A."xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/name"Zhonghua Xue Ye Xue Za Zhi"xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/pages"528-530"xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/title"[Association of HLA-DQB1 alleles and the susceptibility to beta-thalassemia in Guangxi Chinese Zhuang nationality]."xsd:string
http://purl.uniprot.org/citations/11189498http://purl.uniprot.org/core/volume"19"xsd:string
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