http://purl.uniprot.org/citations/11207387 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11207387 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11207387 | http://www.w3.org/2000/01/rdf-schema#comment | "Brain-Muscle-Arnt-Like-protein 2 (BMAL2; Arnt4) (aryl hydrocarbon receptor nuclear translocator) is a recently identified basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor, which contributes to a positive regulation of autoregulatory feedback loop in vertebrate circadian clock systems. In this study, we cloned cDNAs encoding mouse and rat BMAL2 (mBMAL2 and rBMAL2) from mouse midbrain and rat-1 fibroblast cells, respectively. A phylogenetic analysis strongly suggested that vertebrate Bmal1 and Bmal2 genes were generated by a single gene duplication of an ancestral Bmal gene, a vertebrate ortholog of dCyc gene, and that 'BMAL2's putatively termed so far are orthologous. Interestingly, BMAL2 proteins have diverged about 20-fold more rapidly than BMAL1 proteins after the duplication, suggesting an as-yet-unidentified function conserved in BMAL1 but not in BMAL2. mBmal2 mRNA was constitutively expressed throughout the day under light-dark cycle in the mouse hypothalamus containing suprachiasmatic nucleus, the site of the central circadian oscillator in mammals."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0304-3940(01)01581-6"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0304-3940(01)01581-6"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.org/dc/terms/identifier | "doi:10.1016/S0304-3940(01)01581-6"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Sasaki M."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Sasaki M."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Okano T."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Okano T."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Fukada Y."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/author | "Fukada Y."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/name | "Neurosci. Lett."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/name | "Neurosci. Lett."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/pages | "111-114"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/pages | "111-114"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/title | "Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/title | "Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication."xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/volume | "300"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://purl.uniprot.org/core/volume | "300"xsd:string |
http://purl.uniprot.org/citations/11207387 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11207387 |
http://purl.uniprot.org/citations/11207387 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11207387 |
http://purl.uniprot.org/citations/11207387 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11207387 |