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http://purl.uniprot.org/citations/11207387http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11207387http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11207387http://www.w3.org/2000/01/rdf-schema#comment"Brain-Muscle-Arnt-Like-protein 2 (BMAL2; Arnt4) (aryl hydrocarbon receptor nuclear translocator) is a recently identified basic Helix-Loop-Helix-Per-Arnt-Sim (bHLH-PAS) transcription factor, which contributes to a positive regulation of autoregulatory feedback loop in vertebrate circadian clock systems. In this study, we cloned cDNAs encoding mouse and rat BMAL2 (mBMAL2 and rBMAL2) from mouse midbrain and rat-1 fibroblast cells, respectively. A phylogenetic analysis strongly suggested that vertebrate Bmal1 and Bmal2 genes were generated by a single gene duplication of an ancestral Bmal gene, a vertebrate ortholog of dCyc gene, and that 'BMAL2's putatively termed so far are orthologous. Interestingly, BMAL2 proteins have diverged about 20-fold more rapidly than BMAL1 proteins after the duplication, suggesting an as-yet-unidentified function conserved in BMAL1 but not in BMAL2. mBmal2 mRNA was constitutively expressed throughout the day under light-dark cycle in the mouse hypothalamus containing suprachiasmatic nucleus, the site of the central circadian oscillator in mammals."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3940(01)01581-6"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.org/dc/terms/identifier"doi:10.1016/s0304-3940(01)01581-6"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.org/dc/terms/identifier"doi:10.1016/S0304-3940(01)01581-6"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Sasaki M."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Sasaki M."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Okano T."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Okano T."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Fukada Y."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/author"Fukada Y."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/name"Neurosci. Lett."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/name"Neurosci. Lett."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/pages"111-114"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/pages"111-114"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/title"Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/title"Cloning of mouse BMAL2 and its daily expression profile in the suprachiasmatic nucleus: a remarkable acceleration of Bmal2 sequence divergence after Bmal gene duplication."xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/volume"300"xsd:string
http://purl.uniprot.org/citations/11207387http://purl.uniprot.org/core/volume"300"xsd:string
http://purl.uniprot.org/citations/11207387http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11207387
http://purl.uniprot.org/citations/11207387http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11207387
http://purl.uniprot.org/citations/11207387http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11207387