RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/11210938http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11210938http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11210938http://www.w3.org/2000/01/rdf-schema#comment"We have sequenced the entire genome of a virulent field isolate of Sendai virus, the Hamamatsu strain, and compared the sequence with that of a distant related strain, the Z strain. Calculation of synonymous and non-synonymous (amino acid changing) nucleotide substitutions revealed regions where changes were permissive and non-permissive, and the experimentally determined functional region were found to be conserved, showing that important regions for function were conserved during evolution. In the cistron-overlapping regions in the P gene, one reading frame was conserved, whereas the other overlapping frame was flexible. The priority of one frame could be a strategy for evolution of an overlapping gene of RNA viruses. We found that the carboxyl two thirds of the C protein was conserved over the amino-terminal one third, possessing priority to the overlapping P polypeptide. This suggests that the carboxyl two thirds of the C protein have a functional importance. We also found a highly variable region between the L coding frame and the 5' trailer sequence. The relevance of these findings to actual viral replication should be clarified in the future."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.org/dc/terms/identifier"doi:10.1023/a:1008130318633"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.org/dc/terms/identifier"doi:10.1023/a:1008130318633"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Fujii Y."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Fujii Y."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Yoshida T."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Yoshida T."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Kiyotani K."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Kiyotani K."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Sakaguchi T."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/author"Sakaguchi T."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/name"Virus Genes"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/name"Virus Genes"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/pages"47-52"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/pages"47-52"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/title"Conserved and non-conserved regions in the Sendai virus genome: evolution of a gene possessing overlapping reading frames."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/title"Conserved and non-conserved regions in the Sendai virus genome: evolution of a gene possessing overlapping reading frames."xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/11210938http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/11210938http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11210938
http://purl.uniprot.org/citations/11210938http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11210938