| http://purl.uniprot.org/citations/11224562 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11224562 | http://www.w3.org/2000/01/rdf-schema#comment | "The coordinated termination of DNA replication is an important step in the life cycle of bacteria with circular chromosomes, but has only been defined at a molecular level in two systems to date. Here we report the structure of an engineered replication terminator protein (RTP) of Bacillus subtilis in complex with a 21 base pair DNA by X-ray crystallography at 2.5 A resolution. We also use NMR spectroscopic titration techniques. This work reveals a novel DNA interaction involving a dimeric 'winged helix' domain protein that differs from predictions. While the two recognition helices of RTP are in close contact with the B-form DNA major grooves, the 'wings' and N-termini of RTP do not form intimate contacts with the DNA. This structure provides insight into the molecular basis of polar replication fork arrest based on a model of cooperative binding and differential binding affinities of RTP to the two adjacent binding sites in the complete terminator."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.org/dc/terms/identifier | "doi:10.1038/84934"xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Folmer R.H."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Otting G."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Duggin I.G."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Wilce M.C."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Wilce J.A."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Wake R.G."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Vivian J.P."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/author | "Hastings A.F."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/name | "Nat Struct Biol"xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/pages | "206-210"xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/title | "Structure of the RTP-DNA complex and the mechanism of polar replication fork arrest."xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/11224562 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11224562 |
| http://purl.uniprot.org/citations/11224562 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11224562 |
| http://purl.uniprot.org/uniprot/#_P0CI76-mappedCitation-11224562 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11224562 |
| http://purl.uniprot.org/uniprot/P0CI76 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11224562 |