| http://purl.uniprot.org/citations/11228145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11228145 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11228145 | http://www.w3.org/2000/01/rdf-schema#comment | "Initiation of translation at the correct position on messenger RNA is essential for accurate protein synthesis. In prokaryotes, this process requires three initiation factors: IF1, IF2, and IF3. Here we report the crystal structure of a complex of IF1 and the 30S ribosomal subunit. Binding of IF1 occludes the ribosomal A site and flips out the functionally important bases A1492 and A1493 from helix 44 of 16S RNA, burying them in pockets in IF1. The binding of IF1 causes long-range changes in the conformation of H44 and leads to movement of the domains of 30S with respect to each other. The structure explains how localized changes at the ribosomal A site lead to global alterations in the conformation of the 30S subunit."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1057766"xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1057766"xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Hartsch T."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Hartsch T."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Ramakrishnan V."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Ramakrishnan V."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Wimberly B.T."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Wimberly B.T."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Carter A.P."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Carter A.P."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Clemons W.M. Jr."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Clemons W.M. Jr."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Brodersen D.E."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Brodersen D.E."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Morgan-Warren R.J."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/author | "Morgan-Warren R.J."xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/pages | "498-501"xsd:string |
| http://purl.uniprot.org/citations/11228145 | http://purl.uniprot.org/core/pages | "498-501"xsd:string |