| http://purl.uniprot.org/citations/11229403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11229403 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11229403 | http://www.w3.org/2000/01/rdf-schema#comment | "The guanosine triphosphatase Ran stimulates assembly of microtubule asters and spindles in mitotic Xenopus egg extracts. A carboxyl-terminal region of the nuclear-mitotic apparatus protein (NuMA), a nuclear protein required for organizing mitotic spindle poles, mimics Ran's ability to induce asters. This NuMA fragment also specifically interacted with the nuclear transport factor, importin-beta. We show that importin-beta is an inhibitor of microtubule aster assembly in Xenopus egg extracts and that Ran regulates the interaction between importin-beta and NuMA. Importin-beta therefore links NuMA to regulation by Ran. This suggests that similar mechanisms regulate nuclear import during interphase and spindle assembly during mitosis."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1057661"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1057661"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Zheng Y."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Zheng Y."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Adam S.A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Adam S.A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Wilde A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Wilde A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Wiese C."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Wiese C."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Merdes A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Merdes A."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Moore M.S."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/author | "Moore M.S."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/pages | "653-656"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/pages | "653-656"xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/title | "Role of importin-beta in coupling Ran to downstream targets in microtubule assembly."xsd:string |
| http://purl.uniprot.org/citations/11229403 | http://purl.uniprot.org/core/title | "Role of importin-beta in coupling Ran to downstream targets in microtubule assembly."xsd:string |