| http://purl.uniprot.org/citations/11239162 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11239162 | http://www.w3.org/2000/01/rdf-schema#comment | "GADS is an adaptor protein implicated in CD3 signaling because of its ability to link SLP-76 to LAT. A GADS-deficient mouse was generated by gene targeting, and the function of GADS in T cell development and activation was examined. GADS-CD4-CD8-thymocytes exhibited a severe block in proliferation but still differentiated into mature T cells. GADS-thymocytes failed to respond to CD3 cross-linking in vivo and were impaired in positive and negative selection. Immunoprecipitation experiments revealed that the association between SLP-76 and LAT was uncoupled in GADS-thymocytes. These observations indicate that GADS is a critical adaptor for CD3 signaling."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1057176"xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Pham C."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Kanagawa O."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Cheng A.M."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "McGlade J."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Liu S.K."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Yoder J."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/author | "Iizuka Y.M."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/pages | "1987-1991"xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/title | "Requirement for the SLP-76 adaptor GADS in T cell development."xsd:string |
| http://purl.uniprot.org/citations/11239162 | http://purl.uniprot.org/core/volume | "291"xsd:string |
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