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http://purl.uniprot.org/citations/11241183http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11241183http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11241183http://www.w3.org/2000/01/rdf-schema#comment"In the rat pancreatic beta-cell, Na/Ca exchange displays a quite high capacity. The cell is equipped with two alternatively spliced Na/Ca exchanger-1 (NCX1) isoforms, namely NCX1.3 and NCX1.7. To examine the existence of a possible functional difference between these splice variants, they were cloned, together with the heart variant NCX1.1, and expressed in human embryonic kidney-293 (HEK293) and Chinese hamster ovary (CHO) cells. In these two systems, the three splice variants showed a comparable level of intracellular Na+ (Na+(i))-dependent extracellular Ca2+(Ca2+(o)) uptake. Different levels of NCX1.3 and NCX1.7 transcripts were found in four rodent species, together with a marked interspecies difference in Na/Ca exchange activity. Three additional splice variants were found (NCX1.2, NCX1.9 and NCX1.13) in guinea-pigs, hamsters and mice, again in different proportions. Our data provide evidence for the activity of the three NCX1 splice variants. They also show the existence of a differential and species-specific transcription pattern of NCX1 gene products in pancreatic islet cells."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.org/dc/terms/identifier"doi:10.1677/joe.0.1680517"xsd:string
http://purl.uniprot.org/citations/11241183http://purl.org/dc/terms/identifier"doi:10.1677/joe.0.1680517"xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Bollen A."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Bollen A."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Herchuelz A."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Herchuelz A."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Van Eylen F."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/author"Van Eylen F."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/name"J. Endocrinol."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/name"J. Endocrinol."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/pages"517-526"xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/pages"517-526"xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/title"NCX1 Na/Ca exchanger splice variants in pancreatic islet cells."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/title"NCX1 Na/Ca exchanger splice variants in pancreatic islet cells."xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/volume"168"xsd:string
http://purl.uniprot.org/citations/11241183http://purl.uniprot.org/core/volume"168"xsd:string
http://purl.uniprot.org/citations/11241183http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11241183
http://purl.uniprot.org/citations/11241183http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11241183
http://purl.uniprot.org/citations/11241183http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11241183
http://purl.uniprot.org/citations/11241183http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11241183