http://purl.uniprot.org/citations/11250046 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11250046 | http://www.w3.org/2000/01/rdf-schema#comment | "DRB1*15/16 nucleotide polymorphism was analyzed in 68 DR2 positive individuals (18 Mexican Mestizos, 30 Mazatecans and 20 Nahuas), carrying a total of 75 DR2 haplotypes. HLA-DR2 was one of the most frequent specificities detected in Mazatecans and Nahuas with gene frequency (gf) of 0.232 and 0.141, respectively. In these populations DRB1*16 was the most frequent DR2 split (gf = 0.183 in Mazatecans and gf = 0.135 in Nahuas), whereas in Mexican Mestizos the most frequent was DRB1*15 (gf = 0.065). Four DRB1-DQB1 combinations in Mexican Mestizos, two in Mazatecans and one in Nahuas were in linkage disequilibrium. In spite of the restricted polymorphism, there were differences on DRB1*15/16 alleles found in Mexicans. DRB1*1501 a Caucasian allele was predominant in Mexican Mestizos, whereas DRB1*1602 an Amerindian allele was characteristic on Indian populations. An important difference was detected among the Amerindian populations studied since DRB1*1502 was only present in Mazatecans. This data corroborates the restricted polymorphism of DRB1*15/16 and the high frequency of DRB1*16 subtype in autochthonous American populations and suggest that the differences in gene frequencies of DRB1*15/16 alleles could be helpful in distinguishing each of these population."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0198-8859(00)00258-5"xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Flores C."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Arnaiz-Villena A."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Granados J."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Zuniga J."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Martinez-Laso J."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Vargas-Alarcon G."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Gomez-Casado E."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Gamboa R."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/author | "Hernandez-Pacheco G."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/pages | "286-291"xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/title | "Polymorphism and distribution of HLA-DR2 alleles in Mexican populations."xsd:string |
http://purl.uniprot.org/citations/11250046 | http://purl.uniprot.org/core/volume | "62"xsd:string |
http://purl.uniprot.org/citations/11250046 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11250046 |
http://purl.uniprot.org/citations/11250046 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11250046 |
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