http://purl.uniprot.org/citations/11252725 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11252725 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11252725 | http://www.w3.org/2000/01/rdf-schema#comment | "Members of the conserved SNF1/AMP-activated protein kinase (AMPK) family regulate cellular responses to environmental and nutritional stress in eukaryotes. Yeast SNF1 and animal AMPKs form a complex with regulatory SNF4/AMPKgamma and SIP1/SIP2/GAL83/AMPKbeta subunits. The beta-subunits function as target selective adaptors that anchor the catalytic kinase and regulator SNF4/gamma-subunits to their kinase association (KIS) and association with the SNF1 complex (ASC) domains. Here we demonstrate that plant SNF1-related protein kinases (SnRKs) interact with an adaptor-regulator protein, AKINbetagamma, in which an N-terminal KIS domain characteristic of beta-subunits is fused with a C-terminal region related to the SNF4/AMPKgamma proteins. AKINbetagamma is constitutively expressed in plants, suppresses the yeast delta snf4 mutation, and shows glucose-regulated interaction with the Arabidopsis SnRK, AKIN11. Our results suggest that evolution of AKINbetagamma reflects a unique function of SNF1-related protein kinases in plant glucose and stress signalling."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.org/dc/terms/identifier | "doi:10.1093/embo-reports/kve001"xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.org/dc/terms/identifier | "doi:10.1093/embo-reports/kve001"xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Koncz C."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Koncz C."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Kleinow T."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Kleinow T."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Alba M.M."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Alba M.M."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Pages M."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Pages M."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Lumbreras V."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/author | "Lumbreras V."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/pages | "55-60"xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/pages | "55-60"xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/title | "Domain fusion between SNF1-related kinase subunits during plant evolution."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/title | "Domain fusion between SNF1-related kinase subunits during plant evolution."xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/volume | "2"xsd:string |
http://purl.uniprot.org/citations/11252725 | http://purl.uniprot.org/core/volume | "2"xsd:string |