http://purl.uniprot.org/citations/11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11259190 | http://www.w3.org/2000/01/rdf-schema#comment | "Loading of most endogenous peptides on major histocompatibility complex class I molecules is conditional on their transport into the endoplasmic reticulum (ER) by the peptide transporter TAP. We describe an HSV-2/1 cross-reactive cytotoxic T-cell (CTL) epitope that is processed in a TAP1-independent manner in vivo following immunization of TAP1-/-mice with naked DNA or a recombinant vaccinia virus. These data indicated that TAP1-independent processing of endogenous proteins is sufficient to prime CTLs in vivo. TAP1-independent processing of this epitope was not due to ER targeting by signal sequences and exogenous loading of MHC-I molecules and was not influenced by the amino acids flanking this epitope. In contrast, TAP1-/-mice infected with HSV-2 or HSV-2 mutants did not mount a CTL response against this epitope."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.2000.0829"xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Walker C.M."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Lee A.Y."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Selby M.J."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Burke R.L."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Hartog K."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Doe B."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/author | "Paliard X."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/pages | "56-64"xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/title | "Induction of herpes simplex virus gB-specific cytotoxic T lymphocytes in TAP1-deficient mice by genetic immunization but not HSV infection."xsd:string |
http://purl.uniprot.org/citations/11259190 | http://purl.uniprot.org/core/volume | "282"xsd:string |
http://purl.uniprot.org/citations/11259190 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11259190 |
http://purl.uniprot.org/citations/11259190 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11259190 |
http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_F6QHF1-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_Q3U543-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_Q62428-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_Q62429-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_Q64333-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_Q3U6V4-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |
http://purl.uniprot.org/uniprot/#_P21958-mappedCitation-11259190 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11259190 |