| http://purl.uniprot.org/citations/11266362 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11266362 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11266362 | http://www.w3.org/2000/01/rdf-schema#comment | "In chromosomal rearrangements of acute myeloid leukaemia patients the mixed lineage leukaemia (MLL) gene, a human homolog of the Drosophila gene trithorax, is frequently fused to AF10. Here we describe the identification and a functional characterization of the Drosophila homolog dAF10. We show that dAF10 functions in heterochromatin-dependent genomic silencing of position effect variegation, a phenomenon associated with chromosomal rearrangements that cause mosaic expression of euchromatic genes when relocated next to heterochromatin. We also demonstrate that dAF10 can associate with the heterochromatin protein 1 (HP1) in vitro and in vivo. The results indicate that dAF10 is an HP1-interacting component of the heterochromatin-dependent gene silencing pathway, which either contributes to the stability of the heterochromatin complex or to its function."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.org/dc/terms/identifier | "doi:10.1093/embo-reports/kve039"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.org/dc/terms/identifier | "doi:10.1093/embo-reports/kve039"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Gerlach N."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Gerlach N."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Linder B."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Linder B."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Jackle H."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/author | "Jackle H."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/name | "EMBO Rep."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/name | "EMBO Rep"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/pages | "211-216"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/pages | "211-216"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/title | "The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/title | "The Drosophila homolog of the human AF10 is an HP1-interacting suppressor of position effect variegation."xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/11266362 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11266362 |
| http://purl.uniprot.org/citations/11266362 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11266362 |
| http://purl.uniprot.org/citations/11266362 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11266362 |
| http://purl.uniprot.org/citations/11266362 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11266362 |