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http://purl.uniprot.org/citations/11274189http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11274189http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11274189http://www.w3.org/2000/01/rdf-schema#comment"We have characterized a novel Sac domain-containing inositol phosphatase, hSac2. It was ubiquitously expressed but especially abundant in the brain, heart, skeletal muscle, and kidney. Unlike other Sac domain-containing proteins, hSac2 protein exhibited 5-phosphatase activity specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This is the first time that the Sac domain has been reported to possess 5-phosphatase activity. Its 5-phosphatase activity for phosphatidylinositol 4,5-bisphosphate (K(m) = 14.3 microm) was comparable with those of Type II 5-phosphatases. These results imply that hSac2 functions as an inositol polyphosphate 5-phosphatase."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m101579200"xsd:string
http://purl.uniprot.org/citations/11274189http://purl.org/dc/terms/identifier"doi:10.1074/jbc.m101579200"xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Mochizuki Y."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Mochizuki Y."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Minagawa T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Minagawa T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Takenawa T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Takenawa T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Ijuin T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/author"Ijuin T."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/pages"22011-22015"xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/pages"22011-22015"xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/title"Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/title"Identification and characterization of a sac domain-containing phosphoinositide 5-phosphatase."xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/volume"276"xsd:string
http://purl.uniprot.org/citations/11274189http://purl.uniprot.org/core/volume"276"xsd:string
http://purl.uniprot.org/citations/11274189http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11274189
http://purl.uniprot.org/citations/11274189http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11274189