| http://purl.uniprot.org/citations/11277690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11277690 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11277690 | http://www.w3.org/2000/01/rdf-schema#comment | "Coronavirus small envelope protein E has two known biological functions: it plays a pivotal role in virus envelope formation, and the murine coronavirus E protein induces apoptosis in E protein-expressing cultured cells. The E protein is an integral membrane protein. Its C-terminal region extends cytoplasmically in the infected cell and in the virion toward the interior. The N-terminal two-thirds of the E protein is hydrophobic and lies buried within the membrane, but its orientation in the lipid membrane is not known. Immunofluorescent analyses of cells expressing biologically active murine coronavirus E protein with a hydrophilic short epitope tag at the N-terminus showed that the epitope tag was exposed cytoplasmically. Immunoprecipitation analyses of the purified microsomal membrane vesicles that contain the same tagged E protein revealed the N-terminal epitope tag outside the microsomal membrane vesicles. These analyses demonstrated that the epitope tag at the N-terminus of the E protein was exposed cytoplasmically. Our data were consistent with an E protein topology model, in which the N-terminal two-thirds of the transmembrane domain spans the lipid bilayer twice, exposing the C-terminal region to the cytoplasm or virion interior."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.2001.0818"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.2001.0818"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Makino S."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Makino S."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Maeda A."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Maeda A."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Maeda J."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Maeda J."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Repass J.F."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/author | "Repass J.F."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/pages | "163-169"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/pages | "163-169"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/title | "Membrane topology of coronavirus E protein."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/title | "Membrane topology of coronavirus E protein."xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/volume | "281"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://purl.uniprot.org/core/volume | "281"xsd:string |
| http://purl.uniprot.org/citations/11277690 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11277690 |
| http://purl.uniprot.org/citations/11277690 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11277690 |