| http://purl.uniprot.org/citations/11280764 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11280764 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11280764 | http://www.w3.org/2000/01/rdf-schema#comment | "Pancreatic cancer continues to be a major unsolved health problem in the world. The prognosis of pancreatic cancer is extremely poor with a median survival of 3-4 months and the 5-year survival being 1-4%. This poor prognosis is primarily because of a lack of effective therapies, and thus development of new treatment modalities is needed. One of these treatments could involve specific immunotherapy, for which elucidation off the molecular basis of T cell-mediated recognition of cancer cells is required. We report here six different genes and 19 immunogenic epitopes from pancreatic adenocarcinoma cells and T-cell receptor beta usage of HLA-A2-restricted CTL clones reacting to some of these epitopes. Sixteen of 19 epitopes were found to possess the ability to induce HLA-A2-restricted CTL activity in the peripheral blood lymphocytes of patients with pancreatic and also colon adenocarcinomas. These results should provide a scientific basis for the development of specific immunotherapy for pancreatic and colon cancer patients."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Itoh K."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Itoh K."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Ito M."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Saito N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Saito N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Harashima N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Harashima N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Ochi M."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Ochi M."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Shichijo S."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Shichijo S."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Tsuda N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/author | "Tsuda N."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/name | "Cancer Res."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/name | "Cancer Res."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/pages | "2038-2046"xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/pages | "2038-2046"xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/title | "Molecular basis of T cell-mediated recognition of pancreatic cancer cells."xsd:string |
| http://purl.uniprot.org/citations/11280764 | http://purl.uniprot.org/core/title | "Molecular basis of T cell-mediated recognition of pancreatic cancer cells."xsd:string |