| http://purl.uniprot.org/citations/11283354 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11283354 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11283354 | http://www.w3.org/2000/01/rdf-schema#comment | "The assembly of higher order chromatin structures has been linked to the covalent modifications of histone tails. We provide in vivo evidence that lysine 9 of histone H3 (H3 Lys9) is preferentially methylated by the Clr4 protein at heterochromatin-associated regions in fission yeast. Both the conserved chromo- and SET domains of Clr4 are required for H3 Lys9 methylation in vivo. Localization of Swi6, a homolog of Drosophila HP1, to heterochomatic regions is dependent on H3 Lys9 methylation. Moreover, an H3-specific deacetylase Clr3 and a beta-propeller domain protein Rik1 are required for H3 Lys9 methylation by Clr4 and Swi6 localization. These data define a conserved pathway wherein sequential histone modifications establish a "histone code" essential for the epigenetic inheritance of heterochromatin assembly."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1060118"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1060118"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Nakayama J."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Nakayama J."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Allis C.D."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Allis C.D."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Strahl B.D."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Strahl B.D."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Grewal S.I.S."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Grewal S.I.S."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Rice J.C."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/author | "Rice J.C."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/pages | "110-113"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/pages | "110-113"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/title | "Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/title | "Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly."xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/volume | "292"xsd:string |
| http://purl.uniprot.org/citations/11283354 | http://purl.uniprot.org/core/volume | "292"xsd:string |