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| http://purl.uniprot.org/citations/11283371 | http://www.w3.org/2000/01/rdf-schema#comment | "The Drosophila Dmblm locus is a homolog of the human Bloom syndrome gene, which encodes a helicase of the RECQ family. We show that Dmblm is identical to mus309, a locus originally identified in a mutagen-sensitivity screen. One mus309 allele, which carries a stop codon between two of the helicase motifs, causes partial male sterility and complete female sterility. Mutant males produce an excess of XY sperm and nullo sperm, consistent with a high frequency of nondisjunction and/or chromosome loss. These phenotypes of mus309 suggest that Dmblm functions in DNA double-strand break repair. The mutant Dmblm phenotypes were partially rescued by an extra copy of the DNA repair gene Ku70, indicating that the two genes functionally interact in vivo."xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.291.5513.2600"xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/author | "Kusano K."xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/author | "Engels W.R."xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/author | "Johnson-Schlitz D.M."xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/pages | "2600-2602"xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/title | "Sterility of Drosophila with mutations in the Bloom syndrome gene--complementation by Ku70."xsd:string |
| http://purl.uniprot.org/citations/11283371 | http://purl.uniprot.org/core/volume | "291"xsd:string |
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