| http://purl.uniprot.org/citations/11289713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11289713 | http://www.w3.org/2000/01/rdf-schema#comment | "Among Japanese, ossification of the posterior longitudinal ligament of the spine (OPLL) is a leading cause of myelopathy, showing ectopic bone formation in the paravertebral ligament. We have provided genetic evidence that the collagen alpha2 (XI) (COL11A2) locus of chromosome 6 constitutes susceptibility for OPLL. Five distinct single nucleotide polymorphisms (SNPs), identified in COL11A2, were combined to construct possible haplotypes by the use of a maximum likelihood program. Estimated haplotype frequency was compared in OPLL patients and non-OPLL controls. We report a gender-specific association of the COL11AA2 haplotvpe with OPLL. The frequency of the most commonly observed haplotype was significantly higher in male patients (P = 0.0003) compared with controls, but not in female patients (P = 0.21). OPLL is predominantly observed in males. with a prevalence ratio of 2:1, and our gender-specific associations indicate that genetic factors involving COL11A2 play a specific role in the etiology of OPLL exclusively in males."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.org/dc/terms/identifier | "doi:10.1007/s100380170117"xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Matsunaga S."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Inoue I."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Maeda S."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Koga H."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Takeda J."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Komiya S."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Harata S."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Numasawa T."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Sakou T."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Ikari K."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/author | "Furushima K."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/name | "J Hum Genet"xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/pages | "1-4"xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/title | "Gender-specific haplotype association of collagen alpha2 (XI) gene in ossification of the posterior longitudinal ligament of the spine."xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://purl.uniprot.org/core/volume | "46"xsd:string |
| http://purl.uniprot.org/citations/11289713 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11289713 |
| http://purl.uniprot.org/citations/11289713 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11289713 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JL35-mappedCitation-11289713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11289713 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JL78-mappedCitation-11289713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11289713 |
| http://purl.uniprot.org/uniprot/#_P13942-mappedCitation-11289713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11289713 |
| http://purl.uniprot.org/uniprot/#_A0A1U9X7H3-mappedCitation-11289713 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11289713 |