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http://purl.uniprot.org/citations/11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11294566http://www.w3.org/2000/01/rdf-schema#comment"Cellular responses to synthetic peptides from the Liver Stage Antigen-1 (LSA-1) from Plasmodium falciparum were determined in 229 Gabonese children. HLA class I and II typing (by PCR-SSP and -RFLP, respectively) revealed that HLA-A*19, -B*17 (and -B*70), -DRB1*05, -DQA1*0102, -DQB1*0602 and -DPB1*0402 were the most frequent types or alleles at each locus. The DQB1*0201 and DQB1*0301 alleles were present at a higher frequency among IL-6 and IFN-gamma responders to the LSA-Rep and LSA-CTL peptides, respectively, and a higher proportion of these responders carried A*19 or B*53. The DRB1*06 type was positively related to the IL-10 production in response to the LSA-CTL peptide, and responders presented mainly A*2. The specificity A*10 was negatively associated with the cellular response to the LSA-J peptide. These results suggest a degree of genetic regulation of specific immune responses by HLA-A, operating at the pre-erythrocytic stage of development of P. falciparum in this Central African population."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.org/dc/terms/identifier"doi:10.1038/sj.gene.6363713"xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Luty A.J."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Deloron P."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Charron D."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Tamouza R."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Fajardy I."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Marzais F."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Migot-Nabias F."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Danze P.M."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Minh T.N."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/author"Renaut A."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/name"Genes Immun"xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/pages"4-10"xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/title"HLA alleles in relation to specific immunity to liver stage antigen-1 from plasmodium falciparum in Gabon."xsd:string
http://purl.uniprot.org/citations/11294566http://purl.uniprot.org/core/volume"2"xsd:string
http://purl.uniprot.org/citations/11294566http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11294566
http://purl.uniprot.org/citations/11294566http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11294566
http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11294566
http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11294566
http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11294566
http://purl.uniprot.org/uniprot/#_A0A0A7C545-mappedCitation-11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11294566
http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-11294566http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11294566