http://purl.uniprot.org/citations/11297731 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11297731 | http://www.w3.org/2000/01/rdf-schema#comment | "Mac1p is a Saccharomyces cerevisiae DNA binding transcription factor that activates genes involved in copper uptake. A copper-induced N-C-terminal intramolecular interaction and copper-independent homodimerization affect its function. Here, we present a functional analysis of Mac1p deletion derivatives that attributes new roles to the second cysteine-rich (REPII) domain of the protein. This domain exhibits the copper-responsive potent transactivation function when assayed independently and, in the context of the entire protein, modulates the efficiency of Mac1p binding to DNA. The efficiency of binding to both copper-response promoter elements can determine the in vivo functionality of Mac1p independent of homodimerization."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(01)02298-0"xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/author | "Alexandraki D."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/author | "Voutsina A."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/author | "Fragiadakis G.S."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/author | "Boutla A."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/pages | "38-43"xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/title | "The second cysteine-rich domain of Mac1p is a potent transactivator that modulates DNA binding efficiency and functionality of the protein."xsd:string |
http://purl.uniprot.org/citations/11297731 | http://purl.uniprot.org/core/volume | "494"xsd:string |
http://purl.uniprot.org/citations/11297731 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11297731 |
http://purl.uniprot.org/citations/11297731 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11297731 |
http://purl.uniprot.org/uniprot/#_P35192-mappedCitation-11297731 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11297731 |
http://purl.uniprot.org/uniprot/P35192 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/11297731 |