| http://purl.uniprot.org/citations/11301003 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11301003 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11301003 | http://www.w3.org/2000/01/rdf-schema#comment | "Transmembrane B ephrins and their Eph receptors signal bidirectionally. However, neither the cell biological effects nor signal transduction mechanisms of the reverse signal are well understood. We describe a cytoplasmic protein, PDZ-RGS3, which binds B ephrins through a PDZ domain, and has a regulator of heterotrimeric G protein signaling (RGS) domain. PDZ-RGS3 can mediate signaling from the ephrin-B cytoplasmic tail. SDF-1, a chemokine with a G protein-coupled receptor, or BDNF, act as chemoattractants for cerebellar granule cells, with SDF-1 action being selectively inhibited by soluble EphB receptor. This study reveals a pathway that links reverse signaling to cellular guidance, uncovers a novel mode of control for G proteins, and demonstrates a mechanism for selective regulation of responsiveness to neuronal guidance cues."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00297-5"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00297-5"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Lu Q."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Lu Q."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Flanagan J.G."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Flanagan J.G."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Klein R.S."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Klein R.S."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Sun E.E."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/author | "Sun E.E."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/pages | "69-79"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/pages | "69-79"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/title | "Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/title | "Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction."xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/volume | "105"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://purl.uniprot.org/core/volume | "105"xsd:string |
| http://purl.uniprot.org/citations/11301003 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11301003 |
| http://purl.uniprot.org/citations/11301003 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11301003 |