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http://purl.uniprot.org/citations/11301010http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11301010http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11301010http://www.w3.org/2000/01/rdf-schema#comment"BRCA1 interacts in vivo with a novel protein, BACH1, a member of the DEAH helicase family. BACH1 binds directly to the BRCT repeats of BRCA1. A BACH1 derivative, bearing a mutation in a residue that was essential for catalytic function in other helicases, interfered with normal double-strand break repair in a manner that was dependent on its BRCA1 binding function. Thus, BACH1/BRCA1 complex formation contributes to a key BRCA1 activity. In addition, germline BACH1 mutations affecting the helicase domain were detected in two early-onset breast cancer patients and not in 200 matched controls. Thus, it is conceivable that, like BRCA1, BACH1 is a target of germline cancer-inducing mutations."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(01)00304-x"xsd:string
http://purl.uniprot.org/citations/11301010http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(01)00304-x"xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Lane W.S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Lane W.S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Drapkin R."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Drapkin R."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Ganesan S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Ganesan S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Livingston D.M."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Livingston D.M."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Bell D.W."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Bell D.W."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Haber D.A."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Haber D.A."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Cantor S.B."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Cantor S.B."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Grossman S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Grossman S."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Kass E.M."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Kass E.M."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Sgroi D.C."xsd:string
http://purl.uniprot.org/citations/11301010http://purl.uniprot.org/core/author"Sgroi D.C."xsd:string