| http://purl.uniprot.org/citations/11343654 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11343654 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11343654 | http://www.w3.org/2000/01/rdf-schema#comment | "Synaptic neurotransmitter release is restricted to active zones, where the processes of synaptic vesicle tethering, priming to fusion competence, and Ca2+-triggered fusion are taking place in a highly coordinated manner. We show that the active zone components Munc13-1, an essential vesicle priming protein, and RIM1, a Rab3 effector with a putative role in vesicle tethering, interact functionally. Disruption of this interaction causes a loss of fusion-competent synaptic vesicles, creating a phenocopy of Munc13-1-deficient neurons. RIM1 binding and vesicle priming are mediated by two distinct structural modules of Munc13-1. The Munc13-1/RIM1 interaction may create a functional link between synaptic vesicle tethering and priming, or it may regulate the priming reaction itself, thereby determining the number of fusion-competent vesicles."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00272-0"xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00272-0"xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rettig J."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rettig J."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Brose N."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Brose N."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rhee J.S."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rhee J.S."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rosenmund C."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Rosenmund C."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Betz A."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Betz A."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Ashery U."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Ashery U."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Scheuss V."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Scheuss V."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Junge H.J."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Junge H.J."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Thakur P."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/author | "Thakur P."xsd:string |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11343654 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |