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http://purl.uniprot.org/citations/11356193http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11356193http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11356193http://www.w3.org/2000/01/rdf-schema#comment"An integrated approach in protein discovery through the use of multidisciplinary tools was reported. A novel protein, Hcc-1, was identified by analysis of the hepatocellular carcinoma (HCC)-M cell proteome. The assembled EST sequence of the 210 amino acid novel protein was subsequently confirmed by rapid amplification of cDNA ends (RACE). A total of 687 bp at the 5' untranslated region of Hcc-1 was identified. Promoter activity and several upstream open reading frames (uORFs) were demonstrated at this region. Bioinformatics prediction showed that the first 42 amino acids of the protein is a SAP domain with sequence matches to hnRNP from various vertebrate species. The Hcc-1 protein was localized to the cell nucleus while the gene was localized to chromosome 7q22.1. Hcc-1 cDNA level was increased in pancreatic adenocarcinoma. The level was also increased in well-differentiated hepatocellular carcinoma but decreases as the carcinoma progressed to a poorly differentiated stage."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(01)02409-7"xsd:string
http://purl.uniprot.org/citations/11356193http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(01)02409-7"xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Chung M.C.M."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Chung M.C.M."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Lo S.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Lo S.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ong S.-E."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ong S.-E."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ren E.-C."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ren E.-C."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Tan L.K."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Tan L.K."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Choong M.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Choong M.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Liang R.C.M.Y."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Liang R.C.M.Y."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ou K.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Ou K.L."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Seow T.K."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/author"Seow T.K."xsd:string
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11356193http://purl.uniprot.org/core/date"2001"xsd:gYear