| http://purl.uniprot.org/citations/11429115 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11429115 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11429115 | http://www.w3.org/2000/01/rdf-schema#comment | "We report the first study on prevalence of antiretroviral drug-associated resistance mutations in Venezuela. Protease and reverse transcriptase (RT) coding regions were analyzed in DNA samples obtained from 100 HIV-1-infected individuals. Primary resistance mutations to RT inhibitors were identified in 26% of patients treated with these drugs. Transmission of HIV-1-resistant strains was detected in a drug-naive patient (3%). Primary resistance mutations to protease inhibitors (PIs) were present in 9% of the 44 PI-treated patients and in 1 PI-naive individual. Phylogenetic analysis of these samples has resulted in the most extensive survey, to date, of HIV-1 genetic forms circulating in Venezuela. Ninety-nine samples clustered with subtype B, and 1 individual harbored the first B/F recombinant virus reported in Venezuela, with protease clustering with subtype F and RT with subtype B. In addition, this isolate had a new insertion (Glu-34 duplication) in the protease gene."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.org/dc/terms/identifier | "doi:10.1089/088922201750237022"xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.org/dc/terms/identifier | "doi:10.1089/088922201750237022"xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Najera R."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Najera R."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Delgado E."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Delgado E."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Cuevas M.T."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Cuevas M.T."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Osmanov S."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Osmanov S."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Perez-Alvarez L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Perez-Alvarez L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Thomson M.M."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Thomson M.M."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Villahermosa M.L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Villahermosa M.L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Deibis L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Deibis L."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Echeverria G."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Echeverria G."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Leon-Ponte M."xsd:string |
| http://purl.uniprot.org/citations/11429115 | http://purl.uniprot.org/core/author | "Leon-Ponte M."xsd:string |