| http://purl.uniprot.org/citations/11430802 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11430802 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11430802 | http://www.w3.org/2000/01/rdf-schema#comment | "Dystroglycan-dystrophin complexes are believed to have structural and signaling functions by linking extracellular matrix proteins to the cytoskeleton and cortical signaling molecules. Here we characterize a dystroglycan-dystrophin-related protein 2 (DRP2) complex at the surface of myelin-forming Schwann cells. The complex is clustered by the interaction of DRP2 with L-periaxin, a homodimeric PDZ domain-containing protein. In the absence of L-periaxin, DRP2 is mislocalized and depleted, although other dystrophin family proteins are unaffected. Disruption of the DRP2-dystroglycan complex is followed by hypermyelination and destabilization of the Schwann cell-axon unit in Prx(-/-) mice. Hence, the DRP2-dystroglycan complex likely has a distinct function in the terminal stages of PNS myelinogenesis, possibly in the regulation of myelin thickness."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00327-0"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00327-0"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Brophy P.J."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Brophy P.J."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Sherman D.L."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Sherman D.L."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Fabrizi C."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Fabrizi C."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Gillespie C.S."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/author | "Gillespie C.S."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/pages | "677-687"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/pages | "677-687"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/title | "Specific disruption of a Schwann cell dystrophin-related protein complex in a demyelinating neuropathy."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/title | "Specific disruption of a Schwann cell dystrophin-related protein complex in a demyelinating neuropathy."xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://purl.uniprot.org/core/volume | "30"xsd:string |
| http://purl.uniprot.org/citations/11430802 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11430802 |
| http://purl.uniprot.org/citations/11430802 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11430802 |