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http://purl.uniprot.org/citations/11433291http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/11433291http://www.w3.org/2000/01/rdf-schema#comment"Specific recognition of phosphoinositides is crucial for protein sorting and membrane trafficking. Protein transport to the yeast vacuole depends on the Vam7 t-SNARE and its phox homology (PX) domain. Here, we show that the PX domain of Vam7 targets to vacuoles in vivo in a manner dependent on phosphatidylinositol 3-phosphate generation. A novel phosphatidylinositol-3-phosphate-binding motif and an exposed loop that interacts with the lipid bilayer are identified by nuclear magnetic resonance spectroscopy. Conservation of key structural and binding site residues across the diverse PX family indicates a shared fold and phosphoinositide recognition function."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.org/dc/terms/identifier"doi:10.1038/35083000"xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"Overduin M."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"Emr S.D."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"Kutateladze T.G."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"Sato T.K."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"de Beer T."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/author"Cheever M.L."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/date"2001"xsd:gYear
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/name"Nat Cell Biol"xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/pages"613-618"xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/title"Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes."xsd:string
http://purl.uniprot.org/citations/11433291http://purl.uniprot.org/core/volume"3"xsd:string
http://purl.uniprot.org/citations/11433291http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/11433291
http://purl.uniprot.org/citations/11433291http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/11433291
http://purl.uniprot.org/uniprot/P32912#attribution-AC3F7683119DC125019A4B2028FA0EA7http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/11433291
http://purl.uniprot.org/uniprot/#_P32912-mappedCitation-11433291http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/11433291
http://purl.uniprot.org/uniprot/P32912http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/11433291