| http://purl.uniprot.org/citations/11449366 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11449366 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11449366 | http://www.w3.org/2000/01/rdf-schema#comment | "The cytoplasmic adaptor protein SLP-65 (BLNK or BASH) is a critical downstream effector of the B cell antigen receptor (BCR). Tyrosine-phosphorylated SLP-65 assembles intracellular signaling complexes such as the Ca(2 +) initiation complex encompassing phospholipase C-gamma2 and Bruton's tyrosine kinase. It is, however, unclear how the SLP-65 signaling module can be recruited to the plasma membrane. Here we show that following B cell stimulation, SLP-65 associates directly with the BCR signaling subunit, the Ig-alpha / Ig-beta heterodimer. The interaction is mediated by the Src homology 2 domain of SLP-65 and the phosphorylated Ig-alpha tyrosine 204, which is located outside of the immunoreceptor tyrosine-based activation motif. Our data identify an unexpected BCR phosphorylation pattern and indicate that Ig-alpha has the capability to serve as transmembrane adaptor in BCR signaling."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.org/dc/terms/identifier | "doi:10.1002/1521-4141(200107)31:7<2126::aid-immu2126>3.0.co;2-o"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.org/dc/terms/identifier | "doi:10.1002/1521-4141(200107)31:7<2126::aid-immu2126>3.0.co;2-o"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Wollscheid B."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Wollscheid B."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Engels N."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Engels N."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Wienands J."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/author | "Wienands J."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/name | "Eur. J. Immunol."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/pages | "2126-2134"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/pages | "2126-2134"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/title | "Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/title | "Association of SLP-65/BLNK with the B cell antigen receptor through a non-ITAM tyrosine of Ig-alpha."xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://purl.uniprot.org/core/volume | "31"xsd:string |
| http://purl.uniprot.org/citations/11449366 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11449366 |
| http://purl.uniprot.org/citations/11449366 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11449366 |
| http://purl.uniprot.org/citations/11449366 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11449366 |
| http://purl.uniprot.org/citations/11449366 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11449366 |