| http://purl.uniprot.org/citations/11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11454195 | http://www.w3.org/2000/01/rdf-schema#comment | "The Mediator complex is essential for basal and regulated expression of nearly all RNA polymerase II-dependent genes in the Saccharomyces cerevisiae genome. Mediator acts as a bridge, conveying regulatory information from enhancers and other control elements to the promoter. It is now clear that Mediator-like complexes also exist in higher eukaryotic cells and that they have an important role in metazoan transcriptional regulation. However, the exact mechanism of Mediator-dependent transcriptional regulation remains unclear. We review here some recent advances in our understanding of Mediator structure and function. We also discuss a model to account for the functional and evolutionary relationship between yeast and metazoan Mediators. As an appendix to this review, we have created a database, MEDB, in which we have compiled information about all the S. cerevisiae Mediator subunits and their homologues in other eukaryotic cells (http://bio.lundberg.gu.se/medb/)."xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2958.2001.02481.x"xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/author | "Gustafsson C.M."xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/author | "Samuelsson T."xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/name | "Mol Microbiol"xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/pages | "1-8"xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/title | "Mediator--a universal complex in transcriptional regulation."xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://purl.uniprot.org/core/volume | "41"xsd:string |
| http://purl.uniprot.org/citations/11454195 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11454195 |
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| http://purl.uniprot.org/uniprot/#_P39073-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_P38304-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_Q06213-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
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| http://purl.uniprot.org/uniprot/#_P32259-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
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| http://purl.uniprot.org/uniprot/#_P40356-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_P19263-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_P19659-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_P25046-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |
| http://purl.uniprot.org/uniprot/#_P32569-mappedCitation-11454195 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11454195 |