| http://purl.uniprot.org/citations/11472404 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11472404 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11472404 | http://www.w3.org/2000/01/rdf-schema#comment | "GOR (GOR47--1) is an epitope thought to be a host-derived antigen cross-reactive with hepatitis C virus (HCV) since it was isolated from a cDNA library of host animals reactive with sera of HCV-positive patients. An enzyme immunosorbent assay (ELISA) using this epitope as antigen is of sufficient sensitivity and specificity for screening patients with HCV. However, the relationship between GOR47--1 epitope and autoimmune phenomena associated with HCV infection or autoimmune hepatitis is controversial. Here we isolated the human GOR gene and found that the GOR47--1 epitope was not translated in humans due to a single base replacement from chimpanzee. Furthermore, we found some patients who had antibodies against another epitope, which is translated (GOR1--125) in humans, although there was no correlation between the existence of anti-GOR47--1 or anti-GOR1--125 Ab and autoimmune phenomena. Serum IgG levels did not influence the titres of these antibodies. Taken together with the results of several other studies, our finding that the GOR47--1 epitope cannot be translated into a protein suggests that there is little relationship between autoimmunity and the GOR gene product in human beings. We also discuss here the possible mechanism of cross-reactivity between HCV and the GOR gene product."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2249.2001.01508.x"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.org/dc/terms/identifier | "doi:10.1046/j.1365-2249.2001.01508.x"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Iizuka T."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Iizuka T."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Watanabe T."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Watanabe T."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Koike R."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Koike R."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Miyasaka N."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/author | "Miyasaka N."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/name | "Clin. Exp. Immunol."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/name | "Clin. Exp. Immunol."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/pages | "429-434"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/pages | "429-434"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/title | "The GOR gene product cannot cross-react with hepatitis C virus in humans."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/title | "The GOR gene product cannot cross-react with hepatitis C virus in humans."xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/volume | "124"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://purl.uniprot.org/core/volume | "124"xsd:string |
| http://purl.uniprot.org/citations/11472404 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11472404 |
| http://purl.uniprot.org/citations/11472404 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11472404 |