http://purl.uniprot.org/citations/11483588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11483588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11483588 | http://www.w3.org/2000/01/rdf-schema#comment | "The intramembrane cleavage of beta-amyloid precursor protein by gamma-secretase is the final step in the generation of amyloid beta-protein. A 59- or 57-residue C-terminal fragment called CTFgamma is produced concomitantly. Putative CTFgamma generated in rat brain membrane preparations was purified and sequenced. Instead of CTFgamma, shorter 50- and 49-residue fragments were identified. In addition, we found similar C-terminal fragments of beta-amyloid precursor-like proteins 1 and 2; these were also cleaved at corresponding sites. This newly identified cleavage occurs at a site two to five residues inside the cytoplasmic membrane boundary, which is very similar to gamma-secretase-like cleavage of Notch 1."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.c100357200"xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.c100357200"xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Gu Y."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Gu Y."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Sato T."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Sato T."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Dohmae N."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Dohmae N."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Ihara Y."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Ihara Y."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Misonou H."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Misonou H."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Takio K."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/author | "Takio K."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/pages | "35235-35238"xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/pages | "35235-35238"xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/title | "Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch."xsd:string |
http://purl.uniprot.org/citations/11483588 | http://purl.uniprot.org/core/title | "Distinct intramembrane cleavage of the beta-amyloid precursor protein family resembling gamma-secretase-like cleavage of Notch."xsd:string |