| http://purl.uniprot.org/citations/11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11509181 | http://www.w3.org/2000/01/rdf-schema#comment | "Alternative splicing of Wt1 results in the insertion or omission of the three amino acids KTS between zinc fingers 3 and 4. In vitro experiments suggest distinct molecular functions for + and -KTS isoforms. We have generated mouse strains in which specific isoforms have been removed. Heterozygous mice with a reduction of +KTS levels develop glomerulosclerosis and represent a model for Frasier syndrome. Homozygous mutants of both strains die after birth due to kidney defects. Strikingly, mice lacking +KTS isoforms show a complete XY sex reversal due to a dramatic reduction of Sry expression levels. Our data demonstrate distinct functions for the two splice variants and place the +KTS variants as important regulators for Sry in the sex determination pathway."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00453-6"xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Ziegler U."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Schedl A."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Gubler M.C."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Landrock D."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Lutsch G."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Hammes A."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Leheste J.R."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/author | "Guo J.K."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/pages | "319-329"xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/title | "Two splice variants of the Wilms' tumor 1 gene have distinct functions during sex determination and nephron formation."xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/11509181 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11509181 |
| http://purl.uniprot.org/citations/11509181 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11509181 |
| http://purl.uniprot.org/uniprot/P22561#attribution-569A5640D031BB061A30B97B1D11038A | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_A0A0R4J267-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_E0CYK1-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_A2A400-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_A0A8Q0P8A2-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_A2A401-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |
| http://purl.uniprot.org/uniprot/#_A2A404-mappedCitation-11509181 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/11509181 |