| http://purl.uniprot.org/citations/11528422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11528422 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11528422 | http://www.w3.org/2000/01/rdf-schema#comment | "Controlling the number of functional gamma-aminobutyric acid A (GABA(A)) receptors in neuronal membranes is a crucial factor for the efficacy of inhibitory neurotransmission. Here we describe the direct interaction of GABA(A) receptors with the ubiquitin-like protein Plic-1. Furthermore, Plic-1 is enriched at inhibitory synapses and is associated with subsynaptic membranes. Functionally, Plic-1 facilitates GABA(A) receptor cell surface expression without affecting the rate of receptor internalization. Plic-1 also enhances the stability of intracellular GABA(A) receptor subunits, increasing the number of receptors available for insertion into the plasma membrane. Our study identifies a previously unknown role for Plic-1, a modulation of GABA(A) receptor cell surface number, which suggests that Plic-1 facilitates accumulation of these receptors in dendritic membranes."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn0901-908"xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.org/dc/terms/identifier | "doi:10.1038/nn0901-908"xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Smart T.G."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Smart T.G."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Thomas P."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Thomas P."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Wisden W."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Wisden W."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Muller E."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Muller E."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Moss S.J."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Moss S.J."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Bedford F.K."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Bedford F.K."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Kittler J.T."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Kittler J.T."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Triller A."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Triller A."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Merlo D."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Merlo D."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Uren J.M."xsd:string |
| http://purl.uniprot.org/citations/11528422 | http://purl.uniprot.org/core/author | "Uren J.M."xsd:string |