http://purl.uniprot.org/citations/11531409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11531409 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11531409 | http://www.w3.org/2000/01/rdf-schema#comment | "Foamy viruses (FV) are complex retroviruses with additional bel genes located between env and the 3' long-terminal repeat. The functions of the bel 2 and bet genes are unknown and both are dispensable for replication of the prototypic human foamy virus in cell cultures. We examined the function(s) of bel 2 and bet of the distantly related feline foamy virus (FFV) in the proviral context. Mutagenesis was used to alter the Bel 2 and Bet or to abrogate their expression. The Bel 2/Bet mutants showed a 1000-fold reduced viral titer in feline kidney cells; in human 293T cells, viral titer was only about 10-fold reduced compared to wild-type FFV. In both cell types, the Bel 2/Bet mutations resulted in a reduced release of FFV particles. The results indicate that FFV Bet is required for efficient virus replication. The functions of the Bel 2 and Bet proteins are discussed."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.2001.1065"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.2001.1065"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Alke A."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Alke A."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Floetenmeyer M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Floetenmeyer M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Fluegel R.M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Fluegel R.M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Kido K."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Kido K."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Loechelt M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Loechelt M."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Schwantes A."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/author | "Schwantes A."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/pages | "310-320"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/pages | "310-320"xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/title | "The bet gene of feline foamy virus is required for virus replication."xsd:string |
http://purl.uniprot.org/citations/11531409 | http://purl.uniprot.org/core/title | "The bet gene of feline foamy virus is required for virus replication."xsd:string |