| http://purl.uniprot.org/citations/11535825 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11535825 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11535825 | http://www.w3.org/2000/01/rdf-schema#comment | "The TRP (transient receptor potential) superfamily includes a group of subfamilies of channel-like proteins mediating a multitude of physiological signaling processes. The TRP-melastatin (TRPM) subfamily includes the putative tumor suppressor melastatin (MLSN) and is a poorly characterized group of TRP-related proteins. Here, we describe the identification and characterization of an additional TRPM protein TRPM4. We reveal that TRPM4 and MLSN each mediate Ca(2+) entry when expressed in HEK293 cells. Furthermore, we demonstrate that a short form of MLSN (MLSN-S) interacts directly with and suppresses the activity of full-length MLSN (MLSN-L). This suppression seems to result from the inhibition of translocation of MLSN-L to the plasma membrane. We propose that control of translocation through interaction between MLSN-S and MLSN-L represents a mode for regulating ion channel activity."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.191360198"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.191360198"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Montell C."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Montell C."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Xu X.-Z.S."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Xu X.-Z.S."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Gill D.L."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Gill D.L."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Moebius F."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/author | "Moebius F."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/pages | "10692-10697"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/pages | "10692-10697"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/title | "Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/title | "Regulation of melastatin, a TRP-related protein, through interaction with a cytoplasmic isoform."xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/volume | "98"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://purl.uniprot.org/core/volume | "98"xsd:string |
| http://purl.uniprot.org/citations/11535825 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11535825 |
| http://purl.uniprot.org/citations/11535825 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11535825 |