http://purl.uniprot.org/citations/11545720 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11545720 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11545720 | http://www.w3.org/2000/01/rdf-schema#comment | "The N-methyl-D-aspartate (NMDA) subtype of glutamate receptor is important for synaptic plasticity and nervous system development and function. We have used genetic and electrophysiological methods to demonstrate that NMR-1, a Caenorhabditis elegans NMDA-type ionotropic glutamate receptor subunit, plays a role in the control of movement and foraging behavior. nmr-1 mutants show a lower probability of switching from forward to backward movement and a reduced ability to navigate a complex environment. Electrical recordings from the interneuron AVA show that NMDA-dependent currents are selectively disrupted in nmr-1 mutants. We also show that a slowly desensitizing variant of a non-NMDA receptor can rescue the nmr-1 mutant phenotype. We propose that NMDA receptors in C. elegans provide long-lived currents that modulate the frequency of movement reversals during foraging behavior."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.org/dc/terms/identifier | "doi:10.1016/S0896-6273(01)00394-4"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0896-6273(01)00394-4"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Maricq A.V."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Maricq A.V."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Hills T."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Hills T."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Madsen D.M."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Madsen D.M."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Brockie P.J."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Brockie P.J."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Mellem J.E."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/author | "Mellem J.E."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/name | "Neuron"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/pages | "617-630"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/pages | "617-630"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/title | "The C. elegans glutamate receptor subunit NMR-1 is required for slow NMDA-activated currents that regulate reversal frequency during locomotion."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/title | "The C. elegans glutamate receptor subunit NMR-1 is required for slow NMDA-activated currents that regulate reversal frequency during locomotion."xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/volume | "31"xsd:string |
http://purl.uniprot.org/citations/11545720 | http://purl.uniprot.org/core/volume | "31"xsd:string |