http://purl.uniprot.org/citations/11546872 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11546872 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/11546872 | http://www.w3.org/2000/01/rdf-schema#comment | "Bcl-2 family members bearing only the BH3 domain are essential inducers of apoptosis. We identified a BH3-only protein, Bmf, and show that its BH3 domain is required both for binding to prosurvival Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf is sequestered to myosin V motors by association with dynein light chain 2. Certain damage signals, such as loss of cell attachment (anoikis), unleash Bmf, allowing it to translocate and bind prosurvival Bcl-2 proteins. Thus, at least two mammalian BH3-only proteins, Bmf and Bim, function to sense intracellular damage by their localization to distinct cytoskeletal structures."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1062257"xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1062257"xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Huang D.C.S."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Huang D.C.S."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Strasser A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Strasser A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Villunger A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Villunger A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Beaumont J.G."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Beaumont J.G."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Puthalakath H."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Puthalakath H."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "O'Reilly L.A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "O'Reilly L.A."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Cheney R.E."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Cheney R.E."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Coultas L."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/author | "Coultas L."xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/name | "Science"xsd:string |
http://purl.uniprot.org/citations/11546872 | http://purl.uniprot.org/core/name | "Science"xsd:string |