| http://purl.uniprot.org/citations/11546874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11546874 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11546874 | http://www.w3.org/2000/01/rdf-schema#comment | "In mammalian cells, splice junctions play a dual role in mRNA quality control: They mediate selective nuclear export of mature mRNA and they serve as a mark for mRNA surveillance, which subjects aberrant mRNAs with premature termination codons to nonsense-mediated decay (NMD). Here, we demonstrate that the protein RNPS1, a component of the postsplicing complex that is deposited 5' to exon-exon junctions, interacts with the evolutionarily conserved human Upf complex, a central component of NMD. Significantly, RNPS1 triggers NMD when tethered to the 3' untranslated region of beta-globin mRNA, demonstrating its role as a subunit of the postsplicing complex directly involved in mRNA surveillance."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1062786"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1062786"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Lykke-Andersen J."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Lykke-Andersen J."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Steitz J.A."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Steitz J.A."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Shu M.-D."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/author | "Shu M.-D."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/pages | "1836-1839"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/pages | "1836-1839"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/title | "Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/title | "Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1."xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/volume | "293"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://purl.uniprot.org/core/volume | "293"xsd:string |
| http://purl.uniprot.org/citations/11546874 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11546874 |
| http://purl.uniprot.org/citations/11546874 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11546874 |
| http://purl.uniprot.org/citations/11546874 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11546874 |
| http://purl.uniprot.org/citations/11546874 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/11546874 |