| http://purl.uniprot.org/citations/11551508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11551508 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/11551508 | http://www.w3.org/2000/01/rdf-schema#comment | "Nonsense-mediated decay (NMD) eliminates mRNAs that prematurely terminate translation. We used antibody to the nuclear cap binding protein CBP80 or its cytoplasmic counterpart eIF4E to immunopurify RNP containing nonsense-free or nonsense-containing transcripts. Data indicate that NMD takes place in association with CBP80. We defined other components of NMD-susceptible mRNP as CBP20, PABP2, eIF4G, and the NMD factors Upf2 and Upf3. Consistent with the dependence of NMD on translation, the NMD of CBP80-bound mRNA is blocked by cycloheximide or suppressor tRNA. These findings provide evidence that translation can take place in association with CBP80. They also indicate that CBP80-bound mRNA undergoes a "pioneer" round of translation, before CBP80-CBP20 are replaced by eIF4E, and Upf2 and Upf3 proteins dissociate from upstream of exon-exon junctions."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00475-5"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(01)00475-5"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Maquat L.E."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Maquat L.E."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Ishigaki Y."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Ishigaki Y."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Serin G."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/author | "Serin G."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/pages | "607-617"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/pages | "607-617"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/title | "Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/title | "Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20."xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/11551508 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11551508 |
| http://purl.uniprot.org/citations/11551508 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/11551508 |