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http://purl.uniprot.org/citations/11554743 | http://www.w3.org/2000/01/rdf-schema#comment | "We have cloned and sequenced the gene encoding mouse pyruvate carboxylase (mPC) [EC 6.4.1.1]. The coding region contains 19 exons, one 5'-untranslated region exon, and 19 introns in 22 kb of genomic DNA. This gene's exon/intron organization is highly conserved with respect to rat and human PC genes. The mPC gene promoter lacks canonical TATA and CCAAT boxes, in common with a number of housekeeping genes. Transient expressions in COS-1 of a luciferase reporter gene under the control of 5'-nested deletions of the 5'-flanking sequence of the mPC gene have identified the 166-bp minimal sequence required for basal transcription. Alternative splicing at the 5'-untranslated region exon of the mouse PC gene results in the production of two alternate transcripts bearing different 5'-noncoding regions. Both transcripts are highly expressed in kidney and liver and moderately expressed in heart and testis and expressed at a low level in spleen."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.2001.5599"xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/author | "Wallace J.C."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/author | "Jitrapakdee S."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/author | "Sunyakumthorn P."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/author | "Boonsaeng V."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/author | "Petchamphai N."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/date | "2001"xsd:gYear |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/pages | "411-417"xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/title | "Structural and promoter regions of the murine pyruvate carboxylase gene."xsd:string |
http://purl.uniprot.org/citations/11554743 | http://purl.uniprot.org/core/volume | "287"xsd:string |
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